RESUMEN
Las últimas recomendaciones del National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol In Adults (ATP III) consideran que un aumento de la concentración de triglicéridos en suero es un factor de riesgo independiente para la enfermedad coronaria. Los métodos de cuantificación no utilizan un «blanco de glicerol» y cuantifican este alcohol junto con la concentración de triglicéridos, por lo que una deficiencia de glicerol cinasa o una disminución de la capacidad de oxidación de glicerol pueden causar falsas elevaciones de triglicéridos. Se presenta el caso de un niño con falsa hipertrigliceridemia debido a glicerolemia (AU)
Recent recommendations from the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults, considered that an increase in serum triglyceride levels is an independent risk factor for coronary heart disease. Most enzymatic methods used in routine laboratories do not involve a glycerol blank and determine both glycerol and triglycerides. Patients with glycerol-kinase deficiency or decreased ability to oxidize glycerol may be diagnosed with a pseudo-hypertriglyceridemia. We report a case of a child with a pseudo hypertriglyceridemia (falsely elevated triglycerides) due to a hyperglycerolemia (AU)
Asunto(s)
Humanos , Masculino , Niño , Hipertrigliceridemia/etiología , Dislipidemias/etiología , Glicerol Quinasa/deficiencia , Enfermedad Coronaria , Glicerol/análisis , Lipoproteínas/análisis , Diagnóstico DiferencialRESUMEN
Recent recommendations from the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults, considered that an increase in serum triglyceride levels is an independent risk factor for coronary heart disease. Most enzymatic methods used in routine laboratories do not involve a glycerol blank and determine both glycerol and triglycerides. Patients with glycerol-kinase deficiency or decreased ability to oxidize glycerol may be diagnosed with a pseudo-hypertriglyceridemia. We report a case of a child with a pseudo hypertriglyceridemia (falsely elevated triglycerides) due to a hyperglycerolemia.
